Congenital Cardiovascular Anomalies in Twins
نویسندگان
چکیده
منابع مشابه
Congenital cardiovascular anomalies in twins.
G REAT advances have been made during the past 2 decades in methods of diagnosing congenital cardiovascular lesions, and in concepts and technics of their surgical correction. There has been almost no progress, however, in the prevention of such defects because of the paucity of knowledge about their causes. The anomalies in humans appear to be genetically determined in certain instances and to...
متن کاملCongenital anomalies in twins in Aberdeen and Northeast Scotland.
Data with regard to the proportion of congenital malformations found at birth are presented from a survey of 657 pairs of twins of known zygosity and placentation delivered in Aberdeen and Northeast Scotland between 1968 and 1979. There was an excess of malformed individuals from monozygotic (MZ) pairs, but this did not reach statistical significance. The possible effect of monochorionic placen...
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BACKGROUND The risk of congenital anomalies in twins is higher than in singletons, but it is less well reported in relation to chorionicity. The aim of this study was to describe the prevalence of congenital anomalies in twin pregnancies by chorionicity and by major subtype and compare the rates with those in singletons. METHODS The study population included 2329 twin pregnancies (4658 twins)...
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The occurrence of trisomy 13 in twins is very rare. We report a pair of genotypically identical twins with trisomy 13 discordant for major anomalies. This case contributes to the already published data on the contribution of non-genetic factors to the aetiology of congenital malformations in monozygotic twins.
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We used non-invasive high frequency ultrasound to screen N-ethyl-N-nitrosourea mutagenized mouse fetuses for congenital cardiovascular anomalies. We ultrasound scanned 7546 mouse fetuses from 262 mutagenized families, and identified 124 families with cardiovascular defects. Represented were most of the major congenital cardiovascular anomalies seen clinically. The ENU-induced mutations in sever...
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ژورنال
عنوان ژورنال: Circulation
سال: 1959
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.20.3.327